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HeRO Publications 2017-02-28T15:23:38+00:00

Vital signs and their cross-correlation in sepsis and NEC: a study of 1,065 very-low-birth-weight infants in two NICUs. Fairchild KD, Lake DE, Kattwinkel J, Moorman JR, Bateman DA, Grieve PG, Isler JR, Sahni R.
Pediatr Res. (2017) Feb;81(2):315-321. doi: 10.1038/pr.2016.215.

New Technology is Life Saving Voice for Premature or Critically Ill Infants.
Neonatology Today. (2016) Aug; 11(8):12-13.

Early Heart Rate Characteristics Predict Death and Morbidities in Preterm Infants.
Sullivan BA, McClure C, Hicks J, Lake DE, Moorman JR, Fairchild KD.
J Pediatr. (2016) Apr 21. pii: S0022-3476(16)00423-6. doi: 10.1016/j.jpeds.2016.03.042.

Predictive monitoring for sepsis and necrotizing enterocolitis to prevent shock.
Sullivan BA, Fairchild KD.
J Semin Fetal Neonatal Med. (2015) Aug;20(4):255-61. doi: 10.1016/j.siny.2015.03.006. Epub 2015 Mar 29.

Heart Rate Characteristics Index Score: È Utile Nel Predire La Sepsi Neonatale?
Pugni L, Ronchi A, Bizzarri B, Piestrasanta C, Araimo G, Ghirardi B, Casciati MC, Perniciaro S, Casartelli M, Mosca F.
J La Pediatria Medica e Chirurgica – Medical and Surgical Pediatrics. (2015) 37(1):47-8.

Abnormal heart rate characteristics are associated with abnormal neuroimaging and outcomes in extremely low birth weight infants.
Fairchild KD, Sinkin RA, Davalian F, Blackman AE, Swanson JR, Matsumoto JA, Lake DE, Moorman JR, Blackman JA.
J Perinatol. (2014) Feb 20. doi: 10.1038/jp.2014.18.

Infection and Other Clinical Correlates of Abnormal Heart Rate Characteristics in Preterm Infants.
Sullivan BA, Grice SM, Lake DE, Moorman JR, Fairchild KD.
J Pediatr. (2014) Jan 9.

Depressed Heart Rate Variability is Associated with Abnormal EEG, MRI, and Death in Neonates with Hypoxic Ischemic Encephalopathy.
Vergales BD, Zanelli SA, Matsumoto JA, Goodkin HP, Lake DE, Moorman JR, Fairchild KD.
Am J Perinatol. (2013) Dec 17.

Heart rate characteristics in the NICU: what nurses need to know.
Hicks JH, Fairchild KD.
J Adv Neonatal Care. (2013) Dec;13(6):396-401. doi: 10.1097/ANC.0000000000000031.

HeRO monitoring in the NICU: sepsis detection and beyond.
Hicks JH, Fairchild KD.
Infant. (2013) 9(6):187-191.

Complex signals bioinformatics: evaluation of heart rate characteristics monitoring as a novel risk marker for neonatal sepsis.
Lake DE, Fairchild KD, Moorman JR.
J Clin Monit Comput. (2013) Nov 19.

Experiences with the HeRO System for the Past Ten Years.
Maxwell SR.
Neonatology Today. (2013) Oct; 8(10):11-12.

Septicemia mortality reduction in neonates in a heart rate characteristics monitoring trial.
Fairchild KD, Schelonka RL, Kaufman DA, Carlo WA, Kattwinkel J, Porcelli PJ, Navarrete CT, Bancalari E, Aschner JL, Walker MW, Perez JA, Palmer C, Lake DE, O’Shea TM, Moorman JR.
Pediatr Res. (2013) Aug 13. doi: 10.1038/pr.2013.136.

Abnormal heart rate characteristics before clinical diagnosis of necrotizing enterocolitis.
Stone ML, Tatum PM, Weitkamp JH, Mukherjee AB, Attridge J, McGahren ED, Rodgers BM, Lake DE, Moorman JR, Fairchild KD.
J Perinatol. (2013) May 30.

Predictive monitoring for early detection of sepsis in neonatal ICU patients.
Fairchild KD.
Curr Opin Pediatr (2013) Apr;25(2):172-9.

HeRO monitoring to reduce mortality in NICU patients.
Fairchild KD, Aschner JL.
P Research and Reports in Neonatology (2012) Aug 14.

Cytokine Screening identifies NICU patients with Gram-negative bacteremia.
Raynor LL, Saucerman JJ, Akinola MO, Lake DE, Moorman, JR, Fairchild KD.
Pediatrics Res (2012) Mar; 71(3):261-6.

Future Directions in the Evaluation and Management of Neonatal Sepsis
Bhatti M, Chu A, Hageman JR, Schreiber M, Alexandar K.
NeoReviews (2012) Feb; 13(2):e103-e110.

Mortality Reduction by Heart Rate Characteristic Monitoring in Very Low Birth Weight Neonates: A Randomized Trial
Moorman, JR, Carlo WA, Kattwinkel J, Schelonka RL, Porcelli PJ, Navarrete CT, Bancalari E, Aschner JL, Walker MW, Perez JA, Palmer C, Stukenborg GJ, Lake DE, O’Shea TM.
J Pediatrics (2011) Dec; 159(6):900-6.

Cardiovascular oscillations at the bedside: early diagnosis of neonatal sepsis using heart rate characteristics monitoring.
Moorman JR, Delos JB, Flower AA, Cao H, Kovatchev BP, Richman JS, Lake DE.
Physiol Meas. 2011 Nov;32(11):1821-32. doi: 10.1088/0967-3334/32/11/S08. Epub 2011 Oct 25.

Pathogen-induced heart rate changes associated with cholinergic nervous system activation.
Fairchild KD, Srinivasan V, Moorman JR, Gaykema RP, Goehler LE.
Am J Physiol Regul Integr Comp Physiol (2011) Feb;300(2):R330-9.

Heart Rate Characteristics: Physiomarkers for Detection of Late-Onset Neonatal Sepsis
Fairchild KD, O’Shea TM.
Clin Perinatol 37 (2010) 581-598.

Periodic heart rate decelerations in premature infants
Flower AA, Moorman JR, Lake DE, Delos JB.
Exp Bio Med (Maywood) 2010 Apr;235(4):531-8.

Endotoxin depresses heart rate variability in mice: cytokine and steroid effects.
Fairchild KD, Saucerman JJ, Raynor LL, Sivak JA, Xiao Y, Lake DE, Moorman JR.
Am J Physiol Regul Integr Comp Physiol (2009) Oct; 297(4):R1019-27.

Heart rate characteristics and neurodevelopmental outcome in very low birth weight infants
Addison K, Griffin MP, Moorman JR, Lake DE, O’Shea TM.
Journal of Perinatology 2009 Jun 25;doi:10.1038/jp.2009.81.

Nearest-Neighbor and Logistic Regression Analyses of Clinical and Heart Rate Characteristics in the Early Diagnosis of Neonatal Sepsis.
Xiao Y, Griffin P, Lake DE, Moorman JR.
Medical Decision Making 2009 Jun 18;doi:10.1177/0272989X09337791.

Heart rate characteristics and clinical signs in neonatal sepsis.
Griffin MP, Lake DE, O’Shea TM, Moorman JR.
Pediatr Res 2007 Feb;61(2):222-7.

Heart rate characteristics monitoring for neonatal sepsis.
Moorman JR, Griffin MP, Lake DE.
IEEE Trans Biomed Eng 2006 Jan; 53(1): 126-132.

Heart rate characteristics: novel physiomarkers to predict neonatal infection and death.
Griffin MP, Lake DE, Bissonette EA, Harrell FE, O’Shea TM, Moorman JR.
Pediatrics 2005;116:1070-1074.

Heart rate characteristics and laboratory tests in the diagnosis of neonatal sepsis.
Griffin MP, Lake DE, Moorman JR.
Pediatrics 2005;115:937-941.

Increased non-stationarity of neonatal heart rate prior to sepsis and systemic inflammatory response syndrome.
Cao H, Griffin MP, Lake DE, Moorman JR.
Ann Biomed Eng 2004;32:233-244.

Abnormal heart rate characteristics are associated with neonatal mortality.
Griffin MP, O’Shea TM, Bissonette EA, Harrell FE, Lake DE, Moorman JR.
Pediatr Res 2004;55:782-788.

Sample entropy analysis.
Richman JS, Lake DE, Moorman JR.
Methods Enzymol 2004;384:172-84.

Sample asymmetry analysis of heart rate characteristics with application to neonatal sepsis and systemic inflammatory response syndrome.
Kovatchev BP, Farhy LS, Cao H, Griffin MP, Lake DE, Moorman JR.
Pediatr Res 2003;54:892-8.

Abnormal heart rate characteristics preceding neonatal sepsis and sepsis-like illness.
Griffin MP, O’Shea TM, Bissonette EA, Harrell FE, Lake DE, Moorman JR.
Pediatr Res 2003;53:920-926.

Sample entropy analysis of neonatal heart rate variability.
Lake DE, Richman JS, Griffin MP, Moorman JR.
Am J Physiol Regul Integr Comp Physiol 2002;283:R789-797.

Marginal Increase in Cost and Excess Length of Stay Associated With Nosocomial Bloodstream Infections in Surviving Very Low Birth Weight Infants.
Payne NR, Carpenter JH, Badger GJ, Horbar JD, Rogowski J.
Pediatrics 2004;114:348-355.

Comparison and clinical application of frequency domain methods in analysis of neonatal heart rate time series.
Chang KL, Monahan KJ, Griffin MP, Lake DE, Moorman JR.
Ann Biomed Eng 2001;29:764-774.

Toward the early diagnosis of neonatal sepsis and sepsis-like illness using novel heart rate analysis.
Griffin MP, Moorman JR.
Pediatrics 2001;107:97-104.

Physiological time series analysis using approximate entropy and sample entropy.
Richman JS, Moorman JR.
Am J Physiol Heart Circ Physiol 2000;278:H2039-2049.

Probing the order in neonatal heart rate variability.
Nelson JC, Rizwan-uddin, Griffin MP, Moorman JR.
Pediatr Res 1998;43:823-831.

Scaling and ordering of neonatal heart rate variability.
Aghili AA, Rizwan-uddin, Griffin MP, Moorman JR.
Phys Rev Lett 1995;74:1254-1257.

The dynamic range of neonatal heart rate variability.
Griffin MP, Scollan DF, Moorman JR.
J Cardiovasc Electrophysiol 1994;5:112-124.